Antibacterial activities of medicated soaps on selected clinical bacterial isolates
Keywords: Antimicrobial activity, bacteria, soap, active ingredient, MIC, MBC
Soaps have been established generally as cleansing agents because of their antimicrobial activities. The antibacterial activities of three different soaps namely; Sanitol, Premier Cool and No.1 antiseptic were investigated on four test clinical bacterial isolates that were tentatively identified as: Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus spp. Antimicrobial susceptibility test was carried out using the agar disc diffusion technique at concentrations of 400, 200, 100, 50 and 20 mg/mL. Pseudomonas aeruginosa was resistant to all the soaps at all concentrations while the other bacteria were inhibited at various concentrations. The minimum inhibitory concentrations (MIC) ranged from 12.5-100 mg/mL of distilled water for the different isolates while 25 mg/mL of Sanitol and Premier Cool was established as the minimum bactericidal concentration (MBC) against Bacillus spp. Sanitol, having displayed the highest activity at low concentrations, can be considered a good antibacterial agent for cleansing purposes.
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Ughamba, K. T., Erondu, K. E., & Anyanwu, C. U. (2019). Antibacterial activities of medicated soaps on selected clinical bacterial isolates. Journal of Basic Pharmacology and Toxicology, 3(2), 17-20. Retrieved from http://scigreen.com/index.php/JBPT/article/view/61
Original Research Articles
Copyright (c) 2019 Kingsley Tochukwu Ughamba, Kelechi Emmanuella Erondu, Chukwudi Uzoma Anyanwu
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
© The Authors. Published by SciGreen Publications. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).